Journal of Biomedical and Translational Research

About Journal of Biomedical and Translational Research

Journal of Biomedical and Translational Research is the official journal of Research Institute of Veterinary Medicine, Chungbuk National University. Abbreviated title is 'J. Biomed. Transl. Res.'. It was launched in 2000. It contains reviews, original articles, short communications, and case reports, etc, which generally contain overall review on current research issues, results of novel experiment or investigation, rapid publication for research results, examination of clinical cases, and unique experimental procedures or techniques, respectively. It is published only online quarterly in March 31, June 30, September 30 and December 31 each year. Supplement numbers are times published. All of the manuscripts are peer-reviewed.
Original Article

Jun 30, 2021

Neurological and regenerative defects in fresh water planarian exposed to lead

Yong-Jin Kim, Yeon-Hwa Kim, A. A. Dilki Indrachapa Adikari, Ram Prasad Aganja, Juneno So, Young-Joo Yi, Sang-Myeong Lee

J Biomed Transl Res 2021;22(2):71-77.
https://doi.org/10.12729/jbtr.2021.22.2.71

Lead (Pb) is a major heavy metal that augments environmental pollution and is a health risk to living organisms. This study was performed to investigate the effect of lead on characteristics of planarian, Dugesia japonica. Briefly, planarians were cultivated in water containing different concentrations (0–400 mg/L) of Pb, and incubated for varying durations (1, 3, and 5 hr). After termination of the incubation time, motility and seizure-like behaviors (c-like, head-bop, snake-like, and screw-like) of the planarians were count...
Original Article

Jun 30, 2021

Inhibitory effect of an ethanol extract mixture of Aralia elata leaf, Chaenomeles sinensis fruit and Glycyrrhizae radix on Aβ (25–35)-induced memory impairment

Yeon Hee Seong

J Biomed Transl Res 2021;22(2):78-84.
https://doi.org/10.12729/jbtr.2021.22.2.78

The young shoots of Aralia elata, Chaenomeles sinensis fruit and Glycyrrhizae radix are edible and traditionally used as anti-inflammatory and antioxidant agents. The present study was performed to investigate the protective effect of an ethanol extract mixture of these three medicinal plants (ACG) against amyloid β protein (Aβ) (25–35)-induced memory impairment in an ICR mouse model. Memory impairment was induced by intracerebroventricular microinjection ...
Original Article

Jun 30, 2021

Establishment of a chicken challenge model of fowl adenovirus serotype-4 for vaccine verification

Ji-Ye Kim, In-Pil Mo, Bon-Sang Koo

J Biomed Transl Res 2021;22(2):85-91.
https://doi.org/10.12729/jbtr.2021.22.2.85

Fowl adenovirus serotype-4 (FAdV-4) infection, also known as hydropericardium-hepatitis syndrome (HHS), is one of the most prevalent diseases in the Korean poultry industry. Therefore, an effective vaccination against FAdV-4 should be developed for prevention of HHS infection. However, a standard animal model with significant pathologic characteristics has not been established for evaluation of HHS vaccine efficacy. In this study, we comparatively evaluated FAdV-4 pathogenicity from specific-pathogen-free (SPF) chickens using FAdV-4 strain (ADL...
Original Article

Jun 30, 2021

Effects of aluminum on the behavior and regeneration of planarian

Yong-Jin Kim, Yeon-Hwa Kim, A. A. Dilki Indrachapa Adikari, Young-Joo Yi, Sang-Myeong Lee

J Biomed Transl Res 2021;22(2):92-99.
https://doi.org/10.12729/jbtr.2021.22.2.92

Aluminum (Al) is one of the most widely applied metals in various industries. Anthropogenic activities of industrial waste result in increased accumulation of Al in natural water resources and aqueous organisms, leading to increased heavy metal pollution in the environment. This will ultimately associate with health risks to all living beings including humans. The present study addresses the possible toxic effects of Al on the motility and regeneration of planarians, using Dugesia japonica as the experimental animal model. Plan...
Case Report

Jun 30, 2021

A case of canine blepharoconjunctivitis associated with atopic dermatitis

Yoonji Kim, Hyeon-Jin Kim, Ji-Hee Kim, Ji-Hye Lee, Soomin Kim, Se Eun Kim, Taejung Kim, Ha-Jung Kim

J Biomed Transl Res 2021;22(2):100-104.
https://doi.org/10.12729/jbtr.2021.22.2.100

An 8-year-old, spayed female Maltese dog was presented with a one-month history of erythema, swelling and alopecia of periocular region with pruritus. The skin lesions were first detected at the age of three years, but this was the first time that symptoms had appeared in the eyes. Physical examination revealed markedly swollen and erythematous eyelids and conjunctiva including Meibomian glands. In addition, periocular alopecia and tears were identified. Slit lamp microscopy revealed erythema of conjunctiva and swelling of Meibomian glands. The...

CURRENT ISSUE
MOST READ ARTICLE

CURRENT ISSUE: Jun 2021, Vol. 22 , No. 2

Original Article Neurological and regenerative defects in fresh water planarian exposed to lead Yong-Jin Kim, Yeon-Hwa Kim, A. A. Dilki Indrachapa Adikari, Ram Prasad Aganja, Juneno So, Young-Joo Yi, Sang-Myeong Lee J Biomed Transl Res 2021;22(2):71-77. https://doi.org/10.12729/jbtr.2021.22.2.71 HTML PDF PubReader	Original Article Inhibitory effect of an ethanol extract mixture of Aralia elata leaf, Chaenomeles sinensis fruit and Glycyrrhizae radix on Aβ (25–35)-induced memory impairment Yeon Hee Seong J Biomed Transl Res 2021;22(2):78-84. https://doi.org/10.12729/jbtr.2021.22.2.78 HTML PDF PubReader
Original Article Establishment of a chicken challenge model of fowl adenovirus serotype-4 for vaccine verification Ji-Ye Kim, In-Pil Mo, Bon-Sang Koo J Biomed Transl Res 2021;22(2):85-91. https://doi.org/10.12729/jbtr.2021.22.2.85 HTML PDF PubReader	Original Article Effects of aluminum on the behavior and regeneration of planarian Yong-Jin Kim, Yeon-Hwa Kim, A. A. Dilki Indrachapa Adikari, Young-Joo Yi, Sang-Myeong Lee J Biomed Transl Res 2021;22(2):92-99. https://doi.org/10.12729/jbtr.2021.22.2.92 HTML PDF PubReader
Case Report A case of canine blepharoconjunctivitis associated with atopic dermatitis Yoonji Kim, Hyeon-Jin Kim, Ji-Hee Kim, Ji-Hye Lee, Soomin Kim, Se Eun Kim, Taejung Kim, Ha-Jung Kim J Biomed Transl Res 2021;22(2):100-104. https://doi.org/10.12729/jbtr.2021.22.2.100 HTML PDF PubReader

MOST READ ARTICLE

Original Article Echocardiographic evaluation of heart failure in dogs with myxomatous mitral valve disease: a retrospective study Donghyun Han, Dong-Guk Lee, Dong-In Jung J Biomed Transl Res 2018;19(4):79-85. https://doi.org/10.12729/jbtr.2018.19.4.079 HTML PDF PubReader Last 3 months views: 414	Original Article Anti-inflammatory activities of sinensetin on LPS-stimulated L6 skeletal muscle cells Jin-A Kim, Sang Eun Ha, Seong Min Kim, Preethi Vetrivel, Gon Sup Kim, Eun Hee Kim J Biomed Transl Res 2019;20(1):1-7. https://doi.org/10.12729/jbtr.2019.20.1.001 HTML PDF PubReader Last 3 months views: 362
Research Article Artemisia annua extract ameliorates high-fat diet-induced fatty liver by activating AMPK Su-Jin Park, Chul Yung Choi, Jae-Cheon Jeong, Rok-Kyoung Lee, Yong-Pil Hwang J Biomed Transl Res 2020;21(2):59-71. https://doi.org/10.12729/jbtr.2020.21.2.059 HTML PDF PubReader Last 3 months views: 360	Case Report Clindamycin-doxycycline-metronidazole combination therapy in a refractory canine babesiosis case Hyung-Mo An, Joong-Hyun Song, Su-Jin An, DoHyeon Yu, Donghyun Han, Young Joo Kim, Dong-In Jung J Biomed Transl Res 2019;20(3):71-74. https://doi.org/10.12729/jbtr.2019.20.3.071 HTML PDF PubReader Last 3 months views: 342
Short communication The anti-Influenza effect of a water soluble herbal extract from Salvia miltiorrhiza (Danshen) in vivo Eun-Seo Lee, Myun Soo Kim, Prasanna Weeratunga, Hyun-Cheol Lee, Kiramage Chathuranga, Jin Yeul Ma, Hong Ik Kim, Jong-Soo Lee J Biomed Transl Res 2018;19(1):21-25. https://doi.org/10.12729/jbtr.2018.19.1.021 HTML PDF PubReader Last 3 months views: 340	Review Selectins: functional importance as cell adhesion molecule in immune system Yunjeong Noh, Donghyun Cho, Haesu Ko, Dajeong Lim, Han-Ha Chai J Biomed Transl Res 2019;20(4):75-81. https://doi.org/10.12729/jbtr.2019.20.4.075 HTML PDF PubReader Last 3 months views: 327
Review A comprehensive review of hypertrophic cardiomyopathy and arterial thromboembolism in cats Donghyun Han, Dong-In Jung J Biomed Transl Res 2019;20(4):82-90. https://doi.org/10.12729/jbtr.2019.20.4.082 HTML PDF PubReader Last 3 months views: 315	Case report Hematometra in a young Poongsan dog with continuous vulvar hemorrhage Hyun-Sik Kim, Ill-Hwa Kim, Hyun-Gu Kang J Biomed Transl Res 2016;17(4):121-125. https://doi.org/10.12729/jbtr.2016.17.4.121 HTML PDF PubReader Last 3 months views: 301