Journal of Biomedical and Translational Research

About Journal of Biomedical and Translational Research

Journal of Biomedical and Translational Research is the official journal of Research Institute of Veterinary Medicine, Chungbuk National University. Abbreviated title is 'J. Biomed. Transl. Res.'. It was launched in 2000. It contains reviews, original articles, short communications, and case reports, etc, which generally contain overall review on current research issues, results of novel experiment or investigation, rapid publication for research results, examination of clinical cases, and unique experimental procedures or techniques, respectively. It is published only online quarterly in March 31, June 30, September 30 and December 31 each year. Supplement numbers are times published. All of the manuscripts are peer-reviewed.
Original Article

Nov 30, -0001

Histone deacetylase 10 (HDAC10) deacetylates c-Jun and suppresses transcriptional activity

So-Hyun Park, Sang-Myeong Lee

J Biomed Transl Res 2026;27(1):1-9.
https://doi.org/10.12729/jbtr.2026.27.1.1

Histone deacetylase 10 (HDAC10) is implicated in pathological conditions such as cancer and inflammatory diseases. While histone deacetylases (HDACs) primarily regulate gene expression via histone deacetylation, their roles in modifying non-histone substrates, particularly transcription factors, are increasingly recognized as important for disease mechanisms. Although HDAC10 is known to deacetylate nuclear substrates in disease-relevant pathways, its specific non-histone targets remain largely unexplored. Given that the transcription factor act...

CURRENT ISSUE: Mar 2026, Vol. 27 , No. 1

Original Article

Histone deacetylase 10 (HDAC10) deacetylates c-Jun and suppresses transcriptional activity

So-Hyun Park, Sang-Myeong Lee

J Biomed Transl Res 2026;27(1):1-9.
https://doi.org/10.12729/jbtr.2026.27.1.1

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