Journal of Biomedical and Translational Research

About Journal of Biomedical and Translational Research

Journal of Biomedical and Translational Research is the official journal of Research Institute of Veterinary Medicine, Chungbuk National University. Abbreviated title is 'J. Biomed. Transl. Res.'. It was launched in 2000. It contains reviews, original articles, short communications, and case reports, etc, which generally contain overall review on current research issues, results of novel experiment or investigation, rapid publication for research results, examination of clinical cases, and unique experimental procedures or techniques, respectively. It is published only online quarterly in March 31, June 30, September 30 and December 31 each year. Supplement numbers are times published. All of the manuscripts are peer-reviewed.
Original Article

Sep 30, 2020

Synergistic effect of probiotic HP7 and the extracts of Perilla frutescens and Glycyrrhiza glabra to alleviate Helicobacter pylori-induced damages

Hyun-A Lee, Okjin Kim

J Biomed Transl Res 2020;21(3):101-108.
https://doi.org/10.12729/jbtr.2020.21.3.101

The efficacy of standard therapeutic strategies for Helicobacter pylori infection is decreasing over time due to the emergence of drug-resistant strains. At the our previous study, we reported that the lactic acid bacterium Lactobacillus paracasei HP7 isolated from kimchi - a fermented vegetable dish widely consumed in Korea - had inhibitory effects against H. pylori in vitro and in vivo. In this study, we are aimed to investigate the synergistic effect of prob...
Original Article

Sep 30, 2020

Comparative analysis of protein profiles between wild-type and Runx3 null mouse embryonic stem cells lines

Oh Kwang Kwon, Mu Seog Choe, You Mie Lee, Sangkyu Lee, Min Young Lee

J Biomed Transl Res 2020;21(3):109-118.
https://doi.org/10.12729/jbtr.2020.21.3.109

Runt related transcription factors (RUNX), a family of well-known transcription factors, play key regulatory roles in diverse biological processes, such as proliferation, differentiation, and DNA repair. Of RUNX family, RUNX3 is the least well characterized of the three family members. Nevertheless, the role of RUNX3 as a key regulator in essential biological pathways has been reported and inactivation of RUNX3 leads to a variety of disease, such as cancer, via regulation of Wnt signaling and K-ras mutations in many mammalian tissues. Recent st...
Original Article

Sep 30, 2020

The standardization of the Korean-English veterinary medical terminology

Dae Joong Kim

J Biomed Transl Res 2020;21(3):119-124.
https://doi.org/10.12729/jbtr.2020.21.3.119

The standardization of the veterinary terms carried out so that Japanese or Chinese terms established in the Japanese Emperor Era modified into Korean character (Hangeul). The standardization of the terminology has been performed in veterinary medicine as well as various fields of study such as medicine, food sciences, biology, chemistry etc. The most appropriate terms were selected according to ‘the principle of establishment on veterinary medical terminology’ following a comparison between veterinary medical and medical terminology, and r...
Original Article

Sep 30, 2020

Melia azedarach extract exhibits a broad spectrum of antiviral effect in vitro and in vivo

N. A. Nadeeka Nethmini, Myun Soo Kim, Kiramage Chathuranga, Jin Yeul Ma, Hongik Kim, Jong-Soo Lee

J Biomed Transl Res 2020;21(3):125-136.
https://doi.org/10.12729/jbtr.2020.21.3.125

Melia azedarach is commonly used in traditional and folk medicine in Korea and China to treat a variety of diseases including diarrheal, diabetic, rheumatic, and hypertensive disease. The aim of this study was to determine the potential prophylactic and therapeutic effects of Melia azedarach against a broad spectrum of viruses in in vitro cell culture model and the protective effect against different influenza A subtypes in BALB/c mice model. An effective dose of pre-treatment, co-treatment, an...
Case Report

Sep 30, 2020

Use of imatinib mesylate in a dog with meningoencephalitis of unknown etiology

Joong-Hyun Song, Dong-In Jung

J Biomed Transl Res 2020;21(3):137-142.
https://doi.org/10.12729/jbtr.2020.21.3.137

A 4-year-old, female, Maltese dog with bilateral hind limb ataxia was brought to Gyeongsang National University Animal Medical Center (GAMC). Based on the previous medical and imaging records, the patient was presumptively diagnosed with a primary brain tumor of the right temporo-occipital lobe on magnetic resonance imaging (MRI) in a local animal hospital. Hydroxyurea and prednisolone therapy was initiated, and the neurological signs transiently improved. Approximately 5 months after the treatment, ataxia recurred and the patient was referred ...

CURRENT ISSUE
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CURRENT ISSUE: Sep 2020, Vol. 21 , No. 3

Original Article Synergistic effect of probiotic HP7 and the extracts of Perilla frutescens and Glycyrrhiza glabra to alleviate Helicobacter pylori-induced damages Hyun-A Lee, Okjin Kim J Biomed Transl Res 2020;21(3):101-108. https://doi.org/10.12729/jbtr.2020.21.3.101 HTML PDF PubReader	Original Article Comparative analysis of protein profiles between wild-type and Runx3 null mouse embryonic stem cells lines Oh Kwang Kwon, Mu Seog Choe, You Mie Lee, Sangkyu Lee, Min Young Lee J Biomed Transl Res 2020;21(3):109-118. https://doi.org/10.12729/jbtr.2020.21.3.109 HTML PDF PubReader
Original Article The standardization of the Korean-English veterinary medical terminology Dae Joong Kim J Biomed Transl Res 2020;21(3):119-124. https://doi.org/10.12729/jbtr.2020.21.3.119 HTML PDF PubReader	Original Article Melia azedarach extract exhibits a broad spectrum of antiviral effect in vitro and in vivo N. A. Nadeeka Nethmini, Myun Soo Kim, Kiramage Chathuranga, Jin Yeul Ma, Hongik Kim, Jong-Soo Lee J Biomed Transl Res 2020;21(3):125-136. https://doi.org/10.12729/jbtr.2020.21.3.125 HTML PDF PubReader
Case Report Use of imatinib mesylate in a dog with meningoencephalitis of unknown etiology Joong-Hyun Song, Dong-In Jung J Biomed Transl Res 2020;21(3):137-142. https://doi.org/10.12729/jbtr.2020.21.3.137 HTML PDF PubReader

MOST READ ARTICLE

Original Article Anti-inflammatory activities of sinensetin on LPS-stimulated L6 skeletal muscle cells Jin-A Kim, Sang Eun Ha, Seong Min Kim, Preethi Vetrivel, Gon Sup Kim, Eun Hee Kim J Biomed Transl Res 2019;20(1):1-7. https://doi.org/10.12729/jbtr.2019.20.1.001 HTML PDF PubReader Last 3 months views: 240	Case Report Pus leakage into abdominal cavity through oviduct in a Siberian husky with pyometra Ung Rae Cho, Ill Hwa Kim, Dae Youn Hwang, Hyun Gu Kang J Biomed Transl Res 2019;20(4):121-125. https://doi.org/10.12729/jbtr.2019.20.4.121 HTML PDF PubReader Last 3 months views: 231
Original Article Echocardiographic evaluation of heart failure in dogs with myxomatous mitral valve disease: a retrospective study Donghyun Han, Dong-Guk Lee, Dong-In Jung J Biomed Transl Res 2018;19(4):79-85. https://doi.org/10.12729/jbtr.2018.19.4.079 HTML PDF PubReader Last 3 months views: 214	Case Report Clindamycin-doxycycline-metronidazole combination therapy in a refractory canine babesiosis case Hyung-Mo An, Joong-Hyun Song, Su-Jin An, DoHyeon Yu, Donghyun Han, Young Joo Kim, Dong-In Jung J Biomed Transl Res 2019;20(3):71-74. https://doi.org/10.12729/jbtr.2019.20.3.071 HTML PDF PubReader Last 3 months views: 201
Review A comprehensive review of hypertrophic cardiomyopathy and arterial thromboembolism in cats Donghyun Han, Dong-In Jung J Biomed Transl Res 2019;20(4):82-90. https://doi.org/10.12729/jbtr.2019.20.4.082 HTML PDF PubReader Last 3 months views: 200	Review Selectins: functional importance as cell adhesion molecule in immune system Yunjeong Noh, Donghyun Cho, Haesu Ko, Dajeong Lim, Han-Ha Chai J Biomed Transl Res 2019;20(4):75-81. https://doi.org/10.12729/jbtr.2019.20.4.075 HTML PDF PubReader Last 3 months views: 191
Research Article Artemisia annua extract ameliorates high-fat diet-induced fatty liver by activating AMPK Su-Jin Park, Chul Yung Choi, Jae-Cheon Jeong, Rok-Kyoung Lee, Yong-Pil Hwang J Biomed Transl Res 2020;21(2):59-71. https://doi.org/10.12729/jbtr.2020.21.2.059 HTML PDF PubReader Last 3 months views: 170	Original Article Melia azedarach extract exhibits a broad spectrum of antiviral effect in vitro and in vivo N. A. Nadeeka Nethmini, Myun Soo Kim, Kiramage Chathuranga, Jin Yeul Ma, Hongik Kim, Jong-Soo Lee J Biomed Transl Res 2020;21(3):125-136. https://doi.org/10.12729/jbtr.2020.21.3.125 HTML PDF PubReader Last 3 months views: 165