Journal of Biomedical and Translational Research

About Journal of Biomedical and Translational Research

Journal of Biomedical and Translational Research is the official journal of Research Institute of Veterinary Medicine, Chungbuk National University. Abbreviated title is 'J. Biomed. Transl. Res.'. It was launched in 2000. It contains reviews, original articles, short communications, and case reports, etc, which generally contain overall review on current research issues, results of novel experiment or investigation, rapid publication for research results, examination of clinical cases, and unique experimental procedures or techniques, respectively. It is published only online quarterly in March 31, June 30, September 30 and December 31 each year. Supplement numbers are times published. All of the manuscripts are peer-reviewed.
Original Article

Nov 30, -0001

Adipose-derived stem cell (ADSC) exosomal hepatocyte growth factor (HGF) regulates apoptosis and migration in inflammationinduced fibroblasts via AKT-FAK

Taejo Kang, Eunhee Yeon, EunJin Han, Sunyoung Kim, Hyekyung Song, Jiyoung Kim

J Biomed Transl Res 2025;26(3):59-68.
https://doi.org/10.12729/jbtr.2025.26.3.59

Human dermal fibroblasts (HDFs) are critical for maintaining skin integrity and facilitating tissue repair, but are highly susceptible to apoptosis and impaired migration under inflammatory stress. Adipose-derived stem cells (ADSCs) exert regenerative effects primarily through paracrine signals, including exosomes enriched with trophic factors. In this study, we investigated the dual role of ADSC-derived exosomal hepatocyte growth factor (HGF) in regulating fibroblast apoptosis and migration under T cell-mediated inflammatory conditions. Co-cul...
Original Article

Nov 30, -0001

Correlation between left atrial anteroposterior diameter and N-Terminal pro-brain natriuretic peptide (NT-proBNP) in dogs with myxomatous mitral valve disease

Hee-Jin Yeom, Junhyung Lee, Hyun-Ji Do, Jae-Hun Kim, Chul Park

J Biomed Transl Res 2025;26(3):69-77.
https://doi.org/10.12729/jbtr.2025.26.3.69

Myxomatous mitral valve disease (MMVD) is the most prevalent cardiac disease in dogs worldwide. Left atrial enlargement is a prominent feature associated with an increased risk of congestive heart failure in dogs with MMVD. Left atrial anteroposterior diameter (LAD) has been suggested as a supplementary parameter for evaluating LA size in various species. The purpose of our study was to establish a correlation between the left atrial anteroposterior diameter normalized to body weight (LADn) and N-terminal pro-brain natriuretic peptide (NT-proBN...
Case Report

Nov 30, -0001

Esophageal perforation following gastric calibration tube insertion during laparoscopic sleeve gastrectomy

Joo Yong Lee, Young Duck Shin

J Biomed Transl Res 2025;26(3):79-83.
https://doi.org/10.12729/jbtr.2025.26.3.79

Esophageal perforation can be caused by Boerhaave syndrome, foreign body ingestion, trauma, operative injury, or tumors. The condition can be fatal and requires emergency treatment. In this case report, we describe an esophageal perforation following gastric calibration tube insertion during laparoscopic sleeve gastrectomy. The female patient developed an esophageal perforation after gastric calibration tube insertion during laparoscopic sleeve gastrectomy, even though there were no complications during the tube insertion. She had mucosal infla...

CURRENT ISSUE: Sep 2025, Vol. 26 , No. 3

Original Article Adipose-derived stem cell (ADSC) exosomal hepatocyte growth factor (HGF) regulates apoptosis and migration in inflammationinduced fibroblasts via AKT-FAK Taejo Kang, Eunhee Yeon, EunJin Han, Sunyoung Kim, Hyekyung Song, Jiyoung Kim J Biomed Transl Res 2025;26(3):59-68. https://doi.org/10.12729/jbtr.2025.26.3.59 HTML PDF PubReader	Original Article Correlation between left atrial anteroposterior diameter and N-Terminal pro-brain natriuretic peptide (NT-proBNP) in dogs with myxomatous mitral valve disease Hee-Jin Yeom, Junhyung Lee, Hyun-Ji Do, Jae-Hun Kim, Chul Park J Biomed Transl Res 2025;26(3):69-77. https://doi.org/10.12729/jbtr.2025.26.3.69 HTML PDF PubReader
Case Report Esophageal perforation following gastric calibration tube insertion during laparoscopic sleeve gastrectomy Joo Yong Lee, Young Duck Shin J Biomed Transl Res 2025;26(3):79-83. https://doi.org/10.12729/jbtr.2025.26.3.79 HTML PDF PubReader

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