Table 2. Cellular damage induced by MDI, TDI and TMA in the in vitro cell models

Models		MucilAir™			SmallAir™			SmallAir-Asthma™
Groups	Low	Middle	High	Low	Middle	High	Low	Middle	High
	(%)			(%)			(%)
MDI	26.78 ± 1.73	34.43 ± 1.38*	40.05 ± 2.05**,+	29.59 ± 1.07	40.67 ± 0.10a	-	10.54 ± 1.41	14.63 ± 1.02**	16.86 ± 0.65**,+
TDI	5.23 ± 0.25	15.00 ± 0.92**	24.64 ± 0.39**,++	18.41 ± 0.59	19.30 ± 0.75	37.40 ± 0.48**,++	6.09 ± 6.32	7.23 ± 6.63	21.24 ± 0.66**,++
TMA	40.35 ± 0.00	36.40 ± 1.91	-	32.69 ± 1.01	21.51 ± 1.94	24.04 ± 2.36	0.77 ± 0.40	15.66 ± 1.09**	21.26 ± 3.80**,++

%, Cell viability was expressed relative to the control.
Values are expressed as the mean ± S.D.
p<0.05 vs. low; Student t-test was used for statistical analysis.
p<0.05 vs. low;
p<0.01 vs. low;
p<0.05 vs. middle;
p<0.01 vs. middle; one-way ANOVA with Turkey’s HSD was used for statistical analysis.
MDI, methylene diphenyl diisocyanate; TDI, toluene diisocyanate; TMA, trimellitic anhydride; -, out of calculated ranges.