Table 7. Summary of relative organ weight data in rats inhaling diethylbenzene for 90 days (n = 10)

Organs (%) Groups
Control Low (40 ppm) Middle (80 ppm) High (160 ppm)
Male
 Adrenal glands 0.0104 ± 0.00095 0.0106 ± 0.00205 0.0097 ± 0.00169 0.0099 ± 0.00181
 Brain 0.3702 ± 0.02368 0.3684 ± 0.02462 0.3773 ± 0.0267 0.3751 ± 0.031
 Epididymides 0.2784 ± 0.02783 0.2574 ± 0.02353 0.269 ± 0.0201 0.2729 ± 0.02685
 Heart 0.2566 ± 0.01781 0.255 ± 0.01458 0.2467 ± 0.0100 0.2472 ± 0.01353
 Kidneys 0.6099 ± 0.04355 0.5652 ± 0.0369* 0.611 ± 0.01994 0.6215 ± 0.04359
 Liver 2.569 ± 0.09974 2.5058 ± 0.1827 2.5307 ± 0.17815 2.6207 ± 0.17052
 Lung 0.1302 ± 0.02234 0.1244 ± 0.01409 0.1335 ± 0.0112 0.133 ± 0.00759
 Spleen 0.183 ± 0.03525 0.176 ± 0.01983 0.1779 ± 0.01981 0.1864 ± 0.02227
 Testes 0.6711 ± 0.06296 0.6698 ± 0.11129 0.6499 ± 0.08108 0.6832 ± 0.0476
 Thymus 0.0649 ± 0.0077 0.0621 ± 0.01376 0.0615 ± 0.01042 0.0625 ± 0.00878
Female
 Adrenal glands 0.0208 ± 0.00393 0.0216 ± 0.0023 0.0201 ± 0.00225 0.0215 ± 0.00278
 Brain 0.6321 ± 0.03148 0.6556 ± 0.04446 0.6465 ± 0.04283 0.6558 ± 0.04322
 Heart 0.2932 ± 0.02339 0.2934 ± 0.0146 0.283 ± 0.02332 0.293 ± 0.0207
 Kidneys 0.6175 ± 0.03091 0.6113 ± 0.02568 0.6279 ± 0.05103 0.6661 ± 0.06205
 Liver 2.891 ± 0.43007 2.7557 ± 0.18567 2.8588 ± 0.31933 2.9791 ± 0.25669
 Lung 0.1823 ± 0.0157 0.1742 ± 0.01009 0.185 ± 0.01121 0.1805 ± 0.01768
 Ovaries 0.0358 ± 0.00617 0.0337 ± 0.00813 0.0353 ± 0.00594 0.0354 ± 0.00568
 Spleen 0.1934 ± 0.01717 0.1967 ± 0.03446 0.1926 ± 0.00704 0.2028 ± 0.01588
 Thymus 0.0928 ± 0.02763 0.0759 ± 0.01674 0.0876 ± 0.01861 0.0909 ± 0.01662
 Uterus 0.2867 ± 0.08935 0.2968 ± 0.06851 0.2706 ± 0.06434 0.2907 ± 0.10959
Data are expressed as the mean ± S.D.
Dunnett’s LSD test significant at the 0.05 level.
n, number of animals examined.