Table 7. Summary of relative organ weight data in rats inhaling diethylbenzene for 90 days (n = 10)
Organs (%) | Groups |
Control | Low (40 ppm) | Middle (80 ppm) | High (160 ppm) |
Male |
Adrenal glands | 0.0104 ± 0.00095 | 0.0106 ± 0.00205 | 0.0097 ± 0.00169 | 0.0099 ± 0.00181 |
Brain | 0.3702 ± 0.02368 | 0.3684 ± 0.02462 | 0.3773 ± 0.0267 | 0.3751 ± 0.031 |
Epididymides | 0.2784 ± 0.02783 | 0.2574 ± 0.02353 | 0.269 ± 0.0201 | 0.2729 ± 0.02685 |
Heart | 0.2566 ± 0.01781 | 0.255 ± 0.01458 | 0.2467 ± 0.0100 | 0.2472 ± 0.01353 |
Kidneys | 0.6099 ± 0.04355 | 0.5652 ± 0.0369* | 0.611 ± 0.01994 | 0.6215 ± 0.04359 |
Liver | 2.569 ± 0.09974 | 2.5058 ± 0.1827 | 2.5307 ± 0.17815 | 2.6207 ± 0.17052 |
Lung | 0.1302 ± 0.02234 | 0.1244 ± 0.01409 | 0.1335 ± 0.0112 | 0.133 ± 0.00759 |
Spleen | 0.183 ± 0.03525 | 0.176 ± 0.01983 | 0.1779 ± 0.01981 | 0.1864 ± 0.02227 |
Testes | 0.6711 ± 0.06296 | 0.6698 ± 0.11129 | 0.6499 ± 0.08108 | 0.6832 ± 0.0476 |
Thymus | 0.0649 ± 0.0077 | 0.0621 ± 0.01376 | 0.0615 ± 0.01042 | 0.0625 ± 0.00878 |
Female |
Adrenal glands | 0.0208 ± 0.00393 | 0.0216 ± 0.0023 | 0.0201 ± 0.00225 | 0.0215 ± 0.00278 |
Brain | 0.6321 ± 0.03148 | 0.6556 ± 0.04446 | 0.6465 ± 0.04283 | 0.6558 ± 0.04322 |
Heart | 0.2932 ± 0.02339 | 0.2934 ± 0.0146 | 0.283 ± 0.02332 | 0.293 ± 0.0207 |
Kidneys | 0.6175 ± 0.03091 | 0.6113 ± 0.02568 | 0.6279 ± 0.05103 | 0.6661 ± 0.06205 |
Liver | 2.891 ± 0.43007 | 2.7557 ± 0.18567 | 2.8588 ± 0.31933 | 2.9791 ± 0.25669 |
Lung | 0.1823 ± 0.0157 | 0.1742 ± 0.01009 | 0.185 ± 0.01121 | 0.1805 ± 0.01768 |
Ovaries | 0.0358 ± 0.00617 | 0.0337 ± 0.00813 | 0.0353 ± 0.00594 | 0.0354 ± 0.00568 |
Spleen | 0.1934 ± 0.01717 | 0.1967 ± 0.03446 | 0.1926 ± 0.00704 | 0.2028 ± 0.01588 |
Thymus | 0.0928 ± 0.02763 | 0.0759 ± 0.01674 | 0.0876 ± 0.01861 | 0.0909 ± 0.01662 |
Uterus | 0.2867 ± 0.08935 | 0.2968 ± 0.06851 | 0.2706 ± 0.06434 | 0.2907 ± 0.10959 |
Data are expressed as the mean ± S.D.
Dunnett’s LSD test significant at the 0.05 level.
n, number of animals examined.