Table 5. Summary of bronchoalveolar lavage fluid data in rats inhaling diethylbenzene for 90 days (n = 5)
| Parameters | Groups |
| Control | Low (40 ppm) | Middle (80 ppm) | High (160 ppm) |
| Male |
| TC (cells/mL) | 734,200 ± 434,704 | 792,200 ± 338,021 | 687,000 ± 504,003 | 975,600 ± 278,974 |
| MAC% (%) | 97.7936 ± 2 | 98.8439 ± 0 | 99.0122 ± 1 | 98.1659 ± 1 |
| LYM% (%) | 0.3419 ± 0 | 0.3725 ± 0 | 0.2122 ± 0 | 0.6854 ± 0 |
| NEU% (%) | 1.3824 ± 2 | 0.7442 ± 0 | 0.5522 ± 1 | 1.0738 ± 1 |
| EOS% (%) | 0.4821 ± 1 | 0.0394 ± 0 | 0.2233 ± 0 | 0.0749 ± 0 |
| MACA (cells/mL) | 721,593.4 ± 434,455 | 783,280.6 ± 335,412 | 677,579 ± 490,157 | 957,281.2 ± 272,820 |
| LYMA (cells/mL) | 3,499.8 ± 4,692 | 3,285.2 ± 3,187 | 1,728.4 ± 3,016 | 6,251 ± 1,885 |
| NEUA (cells/mL) | 6,462.83 ± 8,117 | 5,328.23 ± 2,315 | 5,694.21 ± 9,108 | 11,146.6 ± 11,320 |
| EOSA (cells/mL) | 2,644.07 ± 2,321 | 305.91 ± 684 | 1,998.37 ± 2,825 | 921.35 ± 2,060 |
| LDH (IU/L) | 71.76 ± 40 | 80.94 ± 43 | 92.88 ± 57 | 69.54 ± 47 |
| TP (g/dL) | 0.0156 ± 0 | 0.0152 ± 0 | 0.0226 ± 0 | 0.019 ± 0 |
| ALB (g/dL) | 0.007 ± 0 | 0.0084 ± 0 | 0.0114 ± 0 | 0.0064 ± 0 |
| Female |
| TC (cells/mL) | 437,000 ± 153,747 | 471,800 ± 86,912 | 417,600 ± 216,571 | 406,000 ± 218,628 |
| MAC% (%) | 99.1772 ± 1 | 99.0613 ± 1 | 85.9168 ± 14 | 98.3978 ± 2 |
| LYM% (%) | 0 ± 0 | 0.129 ± 0 | 0.1306 ± 0 | 0 ± 0 |
| NEU% (%) | 0.3757 ± 0 | 0.5805 ± 1 | 13.6525 ± 14 | 1.1676 ± 2 |
| EOS% (%) | 0.4471 ± 1 | 0.2291 ± 0 | 0.3001 ± 0 | 0.1864 ± 0 |
| MACA (cells/mL) | 433,203.8 ± 152,423 | 467,834.8 ± 89,516 | 376,708.4 ± 218,130 | 397,040.2 ± 207,251 |
| LYMA (cells/mL) | 0 ± 0 | 472.2 ± 1,056 | 690.8 ± 1,020 | 0 ± 0 |
| NEUA (cells/mL) | 1,881.78 ± 2,148 | 2,549.46 ± 2,743 | 39,140.63 ± 29,375 | 7,345.56 ± 12,677 |
| EOSA (cells/mL) | 1,914.32 ± 2,796 | 943.34 ± 934 | 1,060.17 ± 1,042 | 956.91 ± 1,460 |
| LDH (IU/L) | 84.84 ± 21 | 45.48 ± 8 | 52.64 ± 13 | 52.92 ± 9 |
| TP (g/dL) | 0.0276 ± 0 | 0.0128 ± 0 | 0.0134 ± 0 | 0.016 ± 0 |
| ALB (g/dL) | 0.0106 ± 0 | 0.0072 ± 0 | 0.0076 ± 0 | 0.0076 ± 0 |
Data are expressed as the mean ± S.D.
n, number of animals examined; TC, total cells; MAC%, alveolar macrophage relative; LYM%, lymphocyte relative; NEU%, neutrophil relative; EOS%, eosinophil relative; MACA, alveolar macrophage absolute; LYMA, lymphocyte absolute; NEUA, neutrophil absolute; EOSA, eosinophil absolute; LDH, lactate dehydrogenase; TP, total protein; ALB, albumin.