Table 3. Summary of blood biochemistry data in male rats inhaling diethylbenzene for 90 days (n = 10)
Parameters | Groups |
Control | Low (40 ppm) | Middle (80 ppm) | High (160 ppm) |
Na (mmol/L) | 147.42 ± 4.56 | 149.95 ± 4.155 | 143.05 ± 18.055 | 149.48 ± 3.021 |
K (mmol/L) | 5.252 ± 0.3827 | 5.38 ± 0.2043 | 5.201 ± 0.43 | 5.297 ± 0.3325 |
Cl (mmol/L) | 106.45 ± 3.682 | 109.24 ± 3.23 | 104.37 ± 12.805 | 108.34 ± 2.147 |
TP (g/dL) | 6.04 ± 0.366 | 6.02 ± 0.297 | 6.08 ± 0.644 | 6.11 ± 0.42 |
ALB (g/dL) | 3.95 ± 0.196 | 3.98 ± 0.204 | 3.93 ± 0.313 | 3.92 ± 0.22 |
CREA (mg/dL) | 0.384 ± 0.0222 | 0.415 ± 0.0299 | 0.409 ± 0.0458 | 0.402 ± 0.0349 |
BUN (mg/dL) | 17.47 ± 2.874 | 19.68 ± 1.737 | 17.93 ± 1.941 | 19.05 ± 2.32 |
GLU (mg/dL) | 149.79 ± 35.882 | 152.86 ± 20.589 | 165.73 ± 38.972 | 167.59 ± 24.634 |
Ca (mg/dL) | 9.55 ± 0.334 | 9.55 ± 0.36 | 9.5 ± 0.316 | 9.68 ± 0.429 |
IP (mg/dL) | 5.8 ± 0.516 | 6.2 ± 0.476 | 6.23 ± 0.574 | 6.36 ± 0.687 |
TBIL (mg/dL) | –0.005 ± 0.0207 | 0.005 ± 0.0151 | –0.017 ± 0.0216 | –0.018 ± 0.0244 |
TCHO (mg/dL) | 84.37 ± 14.67 | 96.69 ± 12.187 | 96.79 ± 20.897 | 88.69 ± 15.305 |
TG (mg/dL) | 71.78 ± 31.735 | 55.39 ± 19.925 | 47.91 ± 14.067 | 59.44 ± 18.51 |
AST (IU/L) | 150.09 ± 37.835 | 52.8 ± 15.618 | 148.96 ± 56.9 | 132.92 ± 14.409 |
ALT (IU/L) | 42.91 ± 7.243 | 186.35 ± 64.471 | 47.55 ± 9.92 | 48.05 ± 9.594 |
ALP (IU/L) | 274.23 ± 57.055 | 325.66 ± 71.903 | 302.62 ± 83.337 | 388.10 ± 122.569* |
A/G ratio | 1.92 ± 0.199 | 1.95 ± 0.246 | 1.86 ± 0.171 | 1.79 ± 0.11 |
Data are expressed as the mean ± S.D.
Dunnett’s LSD test significant at the 0.05 level.
n, number of animals examined; Na, sodium; K, potassium; Cl, chloride; TP, total protein; ALB, albumin; CREA, creatinine; BUN, blood urea nitrogen; GLU, glucose; Ca, calcium; IP, inorganic phosphorus; TBIL, total bilirubin; TCHO, total cholesterol; TG, triglycerides; AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALP, alkaline phosphatase; A/G ratio, albumin/globulin ratio.