Table 3. IC50 values by cell culture type

IC50 value HepG2 2D HepaRG 2D HepG2 3D HepaRG 3D
Amiodarone HCl IC50 (μM) 44.85 65.47 55.64 109.38
Acetaminophen IC50 (mM) 14.95 7.11 48.43 26.19
IC50, 50% inhibitory concentration.