Table 4. Summary of blood biochemistry data in male mice inhaling 1,2-dichlorobenzene for 90 days
| Parameters | Groups (ppm) |
| Control | T1 (30) | T2 (60) | T3 (120) |
| N | 10 | 10 | 10 | 10 |
| Na (mmol/L) | 147.30 ± 0.941 | 148.99 ± 1.098 | 148.46 ± 2.134 | 147.75 ± 2.249 |
| K (mmol/L) | 5.000 ± 0.1927 | 5.478 ± 0.3193 | 5.450 ± 0.5836 | 5.430 ± 0.4165 |
| Cl (mmol/L) | 113.01 ± 2.213 | 115.44 ± 1.806 | 114.75 ± 2.158 | 114.88 ± 1.635 |
| TP (g/dL) | 3.61 ± 0.120 | 3.65 ± 0.135 | 3.61 ± 0.137 | 3.57 ± 0.116 |
| ALB (g/dL) | 2.97 ± 0.082 | 3.00 ± 0.082 | 2.98 ± 0.114 | 2.93 ± 0.082 |
| CREA (mg/dL) | 0.298 ± 0.0336 | 0.283 ± 0.0316 | 0.282 ± 0.0249 | 0.283 ± 0.0356 |
| BUN (mg/dL) | 31.40 ± 7.358 | 24.86 ± 8.383 | 30.48 ± 10.482 | 35.80 ± 10.832 |
| GLU (mg/dL) | 248.57 ± 21.505 | 231.95 ± 23.266 | 236.96 ± 21.199 | 218.16 ± 28.281 |
| Ca (mg/dL) | 8.32 ± 0.162 | 8.38 ± 0.193 | 8.35 ± 0.227 | 8.33 ± 0.231 |
| IP (mg/dL) | 7.49 ± 1.074 | 7.71 ± 1.411 | 7.60 ± 1.190 | 7.29 ± 1.311 |
| TBIL (mg/dL) | 0.171 ± 0.0360 | 0.192 ± 0.0343 | 0.191 ± 0.0341 | 0.165 ± 0.0314 |
| TCHO (mg/dL) | 149.17 ± 11.516 | 142.49 ± 13.219 | 147.82 ± 10.776 | 149.98 ± 7.924 |
| TG (mg/dL) | 60.66 ± 17.763 | 57.06 ± 18.624 | 65.21 ± 13.763 | 78.57 ± 12.725* |
| AST (IU/L) | 44.03 ± 6.319 | 45.91 ± 9.374 | 46.06 ± 6.730 | 48.30 ± 5.456 |
| ALT (IU/L) | 27.11 ± 5.184 | 29.28 ± 8.397 | 29.55 ± 5.921 | 33.18 ± 5.319 |
| ALP (IU/L) | 166.51 ± 12.384 | 192.05 ± 10.168 | 192.89 ± 11.440** | 205.40 ± 18.207** |
| A/G ratio | 4.66 ± 0.306 | 4.68 ± 0.620 | 4.77 ± 0.538 | 4.60 ± 0.323 |
Data are expressed as the mean ± S.D.
Dunnett’s LSD test significant at the 0.05 level.
Dunnett’s LSD test significant at the 0.01 level.
N, number of animals examined; Na, sodium; K, potassium; Cl, chloride; TP, total protein; ALB, albumin; CREA, creatinine; BUN, blood urea nitrogen; GLU, glucose; Ca, calcium; IP, inorganic phosphorus; TBIL, total bilirubin; TCHO, total cholesterol; TG, triglycerides; AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALP, alkaline phosphatase; A/G ratio, albumin/globulin ratio.