Table 4. Summary of blood biochemistry data in male mice inhaling 1,2-dichlorobenzene for 90 days

Parameters Groups (ppm)
Control T1 (30) T2 (60) T3 (120)
N 10 10 10 10
Na (mmol/L) 147.30 ± 0.941 148.99 ± 1.098 148.46 ± 2.134 147.75 ± 2.249
K (mmol/L) 5.000 ± 0.1927 5.478 ± 0.3193 5.450 ± 0.5836 5.430 ± 0.4165
Cl (mmol/L) 113.01 ± 2.213 115.44 ± 1.806 114.75 ± 2.158 114.88 ± 1.635
TP (g/dL) 3.61 ± 0.120 3.65 ± 0.135 3.61 ± 0.137 3.57 ± 0.116
ALB (g/dL) 2.97 ± 0.082 3.00 ± 0.082 2.98 ± 0.114 2.93 ± 0.082
CREA (mg/dL) 0.298 ± 0.0336 0.283 ± 0.0316 0.282 ± 0.0249 0.283 ± 0.0356
BUN (mg/dL) 31.40 ± 7.358 24.86 ± 8.383 30.48 ± 10.482 35.80 ± 10.832
GLU (mg/dL) 248.57 ± 21.505 231.95 ± 23.266 236.96 ± 21.199 218.16 ± 28.281
Ca (mg/dL) 8.32 ± 0.162 8.38 ± 0.193 8.35 ± 0.227 8.33 ± 0.231
IP (mg/dL) 7.49 ± 1.074 7.71 ± 1.411 7.60 ± 1.190 7.29 ± 1.311
TBIL (mg/dL) 0.171 ± 0.0360 0.192 ± 0.0343 0.191 ± 0.0341 0.165 ± 0.0314
TCHO (mg/dL) 149.17 ± 11.516 142.49 ± 13.219 147.82 ± 10.776 149.98 ± 7.924
TG (mg/dL) 60.66 ± 17.763 57.06 ± 18.624 65.21 ± 13.763 78.57 ± 12.725*
AST (IU/L) 44.03 ± 6.319 45.91 ± 9.374 46.06 ± 6.730 48.30 ± 5.456
ALT (IU/L) 27.11 ± 5.184 29.28 ± 8.397 29.55 ± 5.921 33.18 ± 5.319
ALP (IU/L) 166.51 ± 12.384 192.05 ± 10.168 192.89 ± 11.440** 205.40 ± 18.207**
A/G ratio 4.66 ± 0.306 4.68 ± 0.620 4.77 ± 0.538 4.60 ± 0.323
Data are expressed as the mean ± S.D.
Dunnett’s LSD test significant at the 0.05 level.
Dunnett’s LSD test significant at the 0.01 level.
N, number of animals examined; Na, sodium; K, potassium; Cl, chloride; TP, total protein; ALB, albumin; CREA, creatinine; BUN, blood urea nitrogen; GLU, glucose; Ca, calcium; IP, inorganic phosphorus; TBIL, total bilirubin; TCHO, total cholesterol; TG, triglycerides; AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALP, alkaline phosphatase; A/G ratio, albumin/globulin ratio.