Gender | Group/dosage (mCi/kg) | ||||
---|---|---|---|---|---|
V.C./0 | T1/2.0 | T2/6.0 | T3/18.0 | ||
Male | The number of animal per group | 5 | 5 | 5 | 5 |
The number of animal necropsied | 5 | 5 | 5 | 5 | |
The number of abnormal findings | 0 | 0 | 1 | 3 | |
Gastric atrophy | - | - | 1 | - | |
Fissure | - | - | - | 1 | |
Reduction in spleen size | - | - | - | 2 | |
Female | The number of animal per group | 5 | 5 | 5 | 5 |
The number of animal necropsied | 5 | 5 | 5 | 5 | |
The number of abnormal findings | 1 | 0 | 1 | 2 | |
Gastric atrophy | 1 | - | 1 | - | |
Fissure | - | - | - | 1 | |
Reduction in spleen size | - | - | - | 1 |