Table 5. PK parameters for in vivo tissue distribution (%ID/g) of the Thyrokitty injection (I-131)

	Tmax	Cmax	AUClast	AUCINF_obs	CI_F_obs	MRTlast	MRTINF_obs	HL_Lambda_z1)
Unit	hr	{%ID/g}	hr × {%ID/g}	hr × {%ID/g}	{mCi}/(hr × {%ID/g})/kg	hr	hr	hr
Blood	0.083	6.55	14.93	15.91	0.13	12.01	31.38	109.69
Heart	0.083	1.49	6.66	7.37	0.27	17.43	47.16	110.59
Liver	0.083	1.21	6.80	7.65	0.26	24.21	54.90	92.41
Lung	0.083	2.72	13.70	30.30	0.07	24.21	585.29	610.21
Spleen	0.083	1.50	8.21	9.17	0.22	16.11	51.22	127.74
Kidney	0.083	3.56	12.53	14.38	0.14	34.80	60.08	43.31
Stomach	1	8.01	57.16	58.32	0.03	8.77	14.31	82.48
Small intestine	1	1.22	10.52	11.52	0.17	17.36	43.14	101.08
Large intestine	1	2.34	15.37	17.01	0.12	15.29	48.54	132.16
Muscle	1	1.04	4.64	6.59	0.30	16.41	205.38	337.76
Femur	0.083	1.36	7.04	8.23	0.24	26.36	55.50	41.70
Brain	0.083	0.21	1.15	1.24	1.61	31.03	44.66	34.61
Thyroid	72	58.42	4,532.24	-	-	90.01	-	-
Skin	0.083	25.24	21.21	22.22	0.09	23.33	33.45	52.79
Testis	1	0.79	6.20	6.34	0.32	18.55	23.01	34.86

Terminal half-life of the drug.
PK, pharmacokinetic; ID, injected dose.