Table 1. Grouping, average weight and dosage for in vivo tissue distribution and excretion testing

Group Test substance Administration method Harvest time (hr) The number of animal Planned dosage (mCi/kg) Average weight (g) Actual dosage (µCi) Actual dosage (MBq)
G1 Thyrokitty injection (I-131) S.C. 0.083 (5 min) 4 2 32.91 ± 1.59 73.63 ± 7.93 2.72 ± 0.29
G2 Thyrokitty injection (I-131) S.C. 1 4 2 33.94 ± 0.55 78.66 ± 2.41 2.91 ± 0.09
G3 Thyrokitty injection (I-131) S.C. 6 4 2 33.55 ± 0.99 72.34 ± 11.11 2.68 ± 0.41
G4 Thyrokitty injection (I-131) S.C. 24 4 2 33.36 ± 0.97 71.00 ± 8.82 2.63 ± 0.33
G5 Thyrokitty injection (I-131) S.C. 48 4 2 33.44 ± 0.95 74.00 ± 10.76 2.74 ± 0.40
G6 Thyrokitty injection (I-131) S.C. 72 4 2 33.06 ± 1.14 71.04 ± 9.24 2.63 ± 0.34
G7 Thyrokitty injection (I-131) S.C. 168 4 2 33.32 ± 1.60 72.17 ± 9.85 2.67 ± 0.36
Excretion Thyrokitty injection (I-131) S.C. 6, 24, 48, 72, 120, 168 4 2 33.50 ± 1.16 71.87 ± 9.43 2.66 ± 0.35