Table 1. Mean body weight changes of rats in the 28-day repeated oral dose toxicity study of SUNACTIVE Fe-P80
Items | Dose (mg/kg/day) |
0 | 500 | 1,000 | 2,000 |
No. of males examined | 5 | 5 | 5 | 5 |
Day 0 | 177.1 ± 3.1 | 176.7 ± 6.4 | 173.7 ± 1.9 | 176.4 ± 7.2 |
Day 7 | 231.3 ± 10.5 | 230.4 ± 13.5 | 224.3 ± 9.1 | 238.2 ± 10.5 |
Day 14 | 280.4 ± 14.5 | 281.8 ± 22.5 | 271.3 ± 16.7 | 297.7 ± 16.5 |
Day 21 | 314.2 ± 17.5 | 318.8 ± 28.8 | 305.2 ± 21.7 | 339.1 ± 23.7 |
Day 27 | 339.6 ± 19.5 | 350.6 ± 33.9 | 328.2 ± 26.8 | 366.3 ± 32.8 |
No. of females examined | 5 | 5 | 5 | 5 |
Day 0 | 153.6 ± 6.5 | 151.7 ± 5.8 | 152.4 ± 4.3 | 154.6 ± 2.3 |
Day 7 | 177.6 ± 6.9 | 178.7 ± 11.7 | 180.0 ± 10.9 | 178.3 ± 6.0 |
Day 14 | 204.2 ± 6.4 | 198.6 ± 17.3 | 203.1 ± 19.9 | 197.8 ± 10.6 |
Day 21 | 224.3 ± 8.9 | 214.9 ± 20.6 | 227.1 ± 18.7 | 215.9 ± 8.1 |
Day 27 | 239.2 ± 7.3 | 229.9 ± 22.0 | 243.5 ± 20.9 | 228.9 ± 7.4 |
Values are presented as means ± S.D. (g).