Table 1. Assessment rubric for clinical signs developing in anaphylactoid reactions and anaphylaxis in dogs

Clinical signs	Score
Normal	0
Nose, head, or ear scratching (for less than 3 min); sneezing, coughing; skin reddening	1
Nose, head, or ear scratching (for greater than 3 min); skin reddening; excess salivation	2
Skin rash, vomiting, diarrhea, mania, gait disturbance, unsteadiness of gait	3
Pawing the ground, rolling, impaired mentation, somnolence, hypodynamia, wheezing	4
Urinary and fecal incontinence, hematemesis, hematochezia, breathlessness	5
Death	6

Each dog received a score corresponding to the severity of its clinical signs. Adapted from Mi et al. [6] with CC-BY. Details of each dog received a score corresponding to the severity of its clinical signs are provided in Table 3.