Table 1. Effect of ACG on brain cholinesterase activity in Aβ (25–35)-treated mouse brain

Group Dose (mg/kg) Cholinesterase activity (μmol/h/mg protein)
Sham - 5.1 ± 0.3
Aβ (25–35) 15 nmol/animal 9.3 ± 0.5##
+ ACG 10 8.8 ± 0.2
+ ACG 25 7.5 ± 0.2**
+ ACG 50 7.2 ± 0.3**
Cholinesterase activities in mouse brain homogenates were measured after the passive avoidance test retention trial. Values are expressed as the means ± S.E.M. of acetylthiocholine concentrations hydrolyzed by cholinesterase preparation of brain homogenate for 1 h (n = 6 mice/group).
p<0.01 vs. sham control,
p<0.01 vs. 15 nmol Aβ (25–35) control.