Table 1. Upregulated differentially expressed proteins in Runx3 KO mESCs

Accession Protein name Gene name Sequence coverage [%] KO/WT ratio
J3QN06 ATP-dependent (S)-NAD(P)H-hydrate dehydratase Carkd 11 8.4
A2A848 Peroxisomal acyl-coenzyme A oxidase 1 Acox1 4.3 7.9
A0A087WRI5 Adenylate kinase isoenzyme 6 Taf9 58.5 5.6
B1AY10 Transcriptional repressor NF-X1 Nfx1 2.8 4.9
P26618 Platelet-derived growth factor receptor alpha Pdgfra 2.6 3.4
Q3V3K3 Serine/threonine-protein kinase TAO3 Taok3 6.6 3.4
Q8BXQ2 GPI transamidase component PIG-T Pigt 4.3 3.3
O35709 Ectoderm-neural cortex protein 1 Enc1 4.2 3.1
D3Z2Q7 Hemicentin-1 Hmcn1 0.3 3.0
Q3TLX9 Acid sphingomyelinase-like phosphodiesterase 3b Smpdl3b 16.4 3.0
Q8CFE6 Sodium-coupled neutral amino acid transporter 2 Slc38a2 5.8 3.0
Q6PFV6 Ephrin type-A receptor 5 Epha5 2.9 3.0
Q3UDP9 Monocarboxylate transporter 4 Slc16a3 7.2 3.0
Q9JLB4 Cubilin Cubn 19.1 2.8
A2ARV4 Low-density lipoprotein receptor-related protein 2 Lrp2 7.2 2.7
Q99JB7 Protein amnionless Amn 4.8 2.7
Q9Z1K8 Y+L amino acid transporter 1 Slc7a7 6.7 2.7
P11260 Putative transposase element L1Md-A101/L1Md-A102/L1Md-A2 10.9 2.6
Q3UKA4 Alcohol dehydrogenase 1 Adh1 4.5 2.4
Q99L27 GMP reductase 2 Gmpr2 9.5 2.4
E9PX84 Disabled homolog 2 Dab2 29.6 2.4
A2A5R2 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 Arfgef2 1.7 2.4
D3YYG8 Redox-regulatory protein FAM213A Fam213a 15.4 2.2
Q61609 Sodium-dependent phosphate transporter 1 Slc20a1 2.8 2.2
Q921N7 Transmembrane protein 70, mitochondrial Tmem70 7.9 2.2
Q8K3F7 L-threonine 3-dehydrogenase, mitochondrial Tdh 37 2.1
P15331 Peripherin Prph 4.8 2.1
H3BLI9 TSC22 domain family protein 1 Tsc22d1 31.4 2.1
P02463 Collagen alpha-1(IV) chain Col4a1 2.3 2.0
KO, knockout; mESC, mouse embryonic stem cells; KO/WT, knockout to wild-type ratio.