Table 1. Comparison of organ biodistribution in HER2-positive JIMT-1 cell-bearing mice and healthy marmosets at day 1 after administration of 125I-LCB14-0110. Radioactivity is expressed as % ID/tissue

Organs Tumor bearing mice Healthy marmoset
% ID/tissue Relative organ weight (%) % ID/tissue Relative organ weight (%)
Blood 31.770 ± 10.869 7* 17.743 ± 8.648 7*
Liver 3.809 ± 1.211 5.68 ± 0.40 5.939 ± 2.838 3.15 ± 0.17
Spleen 0.466 ± 0.020 0.58 ± 0.10 0.729 ± 0.090 0.07 ± 0.01
Heart 0.568 ± 0.108 0.48 ± 0.05 0.523 ± 0.273 0.51 ± 0.01
Kidneys 1.195 ± 0.408 1.21 ± 0.08 0.784 ± 0.295 0.55 ± 0.08
Lung 1.111 ± 0.297 0.63 ± 0.04 1.154 ± 0.548 0.43 ± 0.08
Stomach 0.765 ± 0.538 2.18 ± 0.70 0.170 ± 0.006 0.36 ± 0.01
Intestine 3.513 ± 0.905 11.89 ± 0.87 2.650 ± 0.322 2.60 ± 0.79
Blood volume was estimated 7% of total body weight for calculation.