Types | Mole | Expression | Ligands | Function |
---|---|---|---|---|
L-selectin (CD62L) | 65–75 kDa | Various leukocytes | GlyCAM-1, CD34, PSGL-1 | Mediates of leukocyte-endothelial interactions |
E-selectin (CD62E) | 116 kDa | Endothelium activated by inflammatory mediators | ESL-1, CD44, Mac-2BP, PSGL-1 | Recruiting leukocytes to the site of injury |
P-selectin (CD62P) | 140 kDa | Endothelium activated by inflammatory stimuli | ESL-1, PSGL-1 | Initial recruitment of leukocytes to the site of injury during inflammation |