Table 1. Selectin family

Types Mole Expression Ligands Function
L-selectin (CD62L) 65–75 kDa Various leukocytes GlyCAM-1, CD34, PSGL-1 Mediates of leukocyte-endothelial interactions
E-selectin (CD62E) 116 kDa Endothelium activated by inflammatory mediators ESL-1, CD44, Mac-2BP, PSGL-1 Recruiting leukocytes to the site of injury
P-selectin (CD62P) 140 kDa Endothelium activated by inflammatory stimuli ESL-1, PSGL-1 Initial recruitment of leukocytes to the site of injury during inflammation
glyCAM-1, glycosylation-dependent cell adhesion molecule-1; PSGL-1, P-selectin glycoprotein ligand-1; ESL-1, E-selectin ligand-1; Mac-2BP, Mac-2 binding protein.