Table 1
Effect of A. arguta on brain cholinesterase activity in mice
Group | Dose | Cholinesterase activitya (μmol/h/mg protein) |
Control | - | 75.4 ± 4.6 |
Aβ (25-35) | 15 nmol/animal | 93.2 ± 6.3# |
+ A. arguta | 25 mg/kg | 75.2 ± 4.2 |
+ A. arguta | 50 mg/kg | 75.5 ± 5.8 |
+ A. arguta | 100 mg/kg | 67.1 ± 4.8** |
Results are expressed as the means ± S.E.M. of acetylthiocholine concentration hydrolyzed by cholinesterase preparation of brain homogenate for 1 h (n = 8 mice/group).
P<0.05 vs. control
P<0.01 vs. Aβ (25-35) alone.