Table 2
Overall analysis between TNF-α polymorphism (-308, G/A) and susceptibility to autoimmune diseases

Genetic comparison (models)	Population	OR (95% CI)	P	Heterogeneity		Model
				P	I2
G vs. A (allele)	All	0.897 (0.652-1.233)	0.503	<0.001	94.08	Random
G/G+G/A vs.A/A (recessive)	All	0.622 (0.325-1.192)	0.152	<0.001	82.41	Random
G/G vs. G/A+A/A (dominant)	All	1.440 (0.916-2.264)	0.114	<0.001	58.58	Random

Tumor necrosis factor-α, TNF-α; OR, odds ratio; CI, confidence interval