Table 2
Overall analysis between IL-10 polymorphism (-1082, G/A) and susceptibility of AR
Organ | Comparison | Heterogeneity | Association test | Egger's regression p |
p | I2 | Model | OR (95% CI) | p |
All | G vs. A | 0.062 | 40.881 | Fixed | 1.078 (0.912-1.275) | 0.378 | 0.704 |
Renal | G vs. A | 0.345 | 10.943 | Fixed | 0.994 (0.822-1.202) | 0.949 | 0.413 |
Liver | G vs. A | 0.055 | 56.730 | Fixed | 1.436 (1.006-2.050) | 0.046 | 0.227 |
All | A/A+A/G vs. G/G | 0.001 | 63.744 | Random | 1.036 (0.629-1.706) | 0.890 | 0.644 |
Renal | A/A+A/G vs. G/G | 0.001 | 72.404 | Random | 0.960 (0.483-1.906) | 0.907 | 0.87 |
Liver | A/A+A/G vs. G/G | 0.328 | 13.459 | Fixed | 1.436 (0.868-2.375) | 0.159 | 0.227 |
AR: acute rejection; OR, odds ratio; CI, confidence interval.