Table 1
Effect of SSB on MCAO/reperfusion-induced behavioral deficits in rats
Group | Dose (mg/kg) | Neurological score |
Vehicle | - | 3.6 ± 0.2 |
SSB | 5 | 2.5 ± 0.2 |
SSB | 10 | 2.2 ± 0.3* |
SSB | 25 | 1.9 ± 0.3** |
After MCAO/reperfusion, neurological status of the animals used in Fig. 1 was evaluated. Five categories of neurological finding according to Menzies were scored: 0, no apparent deficits; 1, contralateral forelimb flection; 2, decreased grip of contralateral forelimb; 3, contralateral circling if pulled by tail; and 4, spontaneous contralateral circling. Values are expressed as mean ± S.E.M.
P<0.05,
P<0.01 vs. vehicle.