Table 2.
Association between GATA5 methylation and clinicopathological characteristics

Variables Methylation level (%) p-value
Normal vs. cancer Normal 17.6 ± 3.6 <0.0011)
Cancer 53.6 ± 24.7
Number of tumors Single 50.9 ± 26.1 0.0811)
Multiple 57.5 ± 22.0
Tumor size <3 cm 51.2 ± 25.5 0.2361)
≥3 cm 56.1 ± 24.0
Grade G1 46.4 ± 24.7 0.0032)
G2 54.3 ± 23.7
G3 67.0 ± 23.3
T stage Ta 44.8 ± 26.0 0.0011)
T1 58.9 ± 22.4
Recurrence No 43.6 ± 23.3 0.0021)
Yes 57.6 ± 24.6
Progression No 51.7 ± 24.1 0.0121)
Yes 68.7 ± 24.7
P-value calculated using Student’s t-test.
P-value calculated using ANOVA trend analyses test. GATA5, GATA binding protein 5.