Table 2.
Association between GATA5 methylation and clinicopathological characteristics
Variables | Methylation level (%) | p-value |
Normal vs. cancer | Normal | 17.6 ± 3.6 | <0.0011) |
| Cancer | 53.6 ± 24.7 | |
Number of tumors | Single | 50.9 ± 26.1 | 0.0811) |
| Multiple | 57.5 ± 22.0 | |
Tumor size | <3 cm | 51.2 ± 25.5 | 0.2361) |
| ≥3 cm | 56.1 ± 24.0 | |
Grade | G1 | 46.4 ± 24.7 | 0.0032) |
| G2 | 54.3 ± 23.7 | |
| G3 | 67.0 ± 23.3 | |
T stage | Ta | 44.8 ± 26.0 | 0.0011) |
| T1 | 58.9 ± 22.4 | |
Recurrence | No | 43.6 ± 23.3 | 0.0021) |
| Yes | 57.6 ± 24.6 | |
Progression | No | 51.7 ± 24.1 | 0.0121) |
| Yes | 68.7 ± 24.7 | |
P-value calculated using Student’s t-test.
P-value calculated using ANOVA trend analyses test. GATA5, GATA binding protein 5.