Table 4.
Changes in wound size (WS)

Wound sizes (mm2)	Control	Madecassol™ 100 mg/kg	β-glucan-applied groups
			10 mg/kg	50 mg/kg	100 mg/kg
			Day 01)	86.07 ± 5.34	86.16 ± 4.80	86.34 ± 4.81	86.58 ± 3.84	86.31 ± 4.40
Day 2	84.10 ± 5.93	83.15 ± 4.89	83.05 ± 4.69	83.77 ± 4.42	84.07 ± 5.45
Day 4	81.16 ± 6.17	78.58 ± 3.75	80.47 ± 5.22	78.08 ± 7.30	77.62 ± 5.20
Day 8	76.88 ± 5.78	69.89 ± 7.49	73.85 ± 6.97	66.01 ± 7.14*	63.17 ± 5.39*
Day 12	69.16 ± 5.41	60.13 ± 9.53**	63.38 ± 8.58	58.81 ± 8.97*	51.51 ± 6.86*
Day 16	57.75 ± 4.77	48.12 ± 9.51**	51.60 ± 6.72**	47.21 ± 10.01**	43.62 ± 7.51*
Day 202)	44.71 ± 7.08	35.25 ± 8.05*	37.16 ± 7.40**	33.41 ± 8.14*	31.70 ± 6.30*
WS % changes (%)3)	– 47.97 ± 8.03	– 59.03 ± 9.25*	– 57.13 ± 6.97**	– 61.44 ± 8.78*	– 63.24 ± 7.02*
CT50(days)4)	28.35 ± 10.65	19.82 ± 5.68**	20.55 ± 3.27**	17.58 ± 3.75*	15.57 ± 2.55*

n=10; (Mean ± S.D.);
Before initial application of test article 1 day after wounding;
Before sacrifice;
% changes in wound size from day 0 to day 20;
50% contraction time of wound; *p<0.01 and **p<0.05 compared to that of control by MW test.