Table 3.
Urine analysis of the neonatal puppies exposed to cold stress factor for monitoring the disease progression of canine herpesvirus (CHV)

Item of Analysis	Group
	CHV-infected		Non-infected
	Cold stress	Hyperthermal	Cold stress	Hyperthermal
Glucose (mg/dL)	859 ± 27.1*	181 ± 9.5	0 ± 0	0 ± 0
Bililubin (gradeb)	2.5 ± 0.55*	0.2 ± 0.05	0 ± 0	0 ± 0
Ketone (mg/dL)	65 ± 10.5*	2 ± 0.5	0 ± 0	0 ± 0
Segment deposition (gradeb)	1.025 ± 0.005	1.010 ± 0.025	1.005 ± 0.001	1.002 ± 0.002
Blood (cells/uL)	200 ± 2.5*	15 ± 2.9	0 ± 0	0 ± 0
pH	6.2 ± 0.35	6.3 ± 0.90	6.5 ± 0.55	6.8 ± 0.25
Protein (mg/dL)	985 ± 49.38	35 ± 1.9	0 ± 0	0 ± 0
Urobilinogen (mg/dL)	8 ± 0.1*	1.5 ± 0.9	0 ± 0	0 ± 0
Nitrogen (gradeb)	3 ± 0.5	1 ± 0.7	0 ± 0	0 ± 0
Leukocyte (cells/uL)	488 ± 52.3*	35 ± 10.9	0 ± 0	0 ± 0

Urine analysis was performed with Multistex 10 SG (Bayer) following manufacturer’s instruction.
It was calculated with average values of individual grade scores converted from following method: − (0); + (1); ++ (2); +++ (3).