Table 1.
Comparison of hair regrowth intensity in C57BL/6 mice
Days | Ctrl | MIN | ET20 | ET40 | FR20 | FR40 |
6 | − | − | − | − | + | + |
9 | − | − | − | − | ++ | ++ |
12 | + | ++ | + | + | +++ | +++ |
15 | ++ | +++ | +++ | +++ | ++++ | ++++ |
21 | ++++ | +++++ | +++++ | +++++ | +++++ | +++++ |
Study compounds were applied to the shaved dorsal skin of mice for 21 days, and hair growth was evaluated by the scoring index: 0~10%(−), 11~30% (+), 31~50% (++), 51~70% (+++), 71~90% (+++), 90~100% (+++++). Ctrl, non-treated normal; MIN, minoxidil 5%; ET20/40, ethanol extract 20/40 mg/kg; FR20/40, fraction 20/40 mg/kg.