Table 2.
Effect of matrigel-based HA/PCL scaffold with osteogenic, angiogenic factors and mesenchymal stem cell on bone volume and bone mineral density in a rat segmental defect model at 8 weeks after surgery

Group Bone Volume (%) Bone mineral density (g/mm3)
Control 14.918 ± 2.710 0.201 ± 0.115
Matrigel 26.760 ± 1.493 0.264 ± 0.023
M + B 26.529 ± 2.255 0.196 ± 0.013
M + B + V 28.800 ± 6.436* 0.260 ± 0.043
MSC 30.790 ± 5.954* 0.235 ± 0.058
P<0.05 as compared with the Control group.
Values are expressed in mean ± S.D. (n=6).
Control=no graft with 5 mm femoral segmental defect; Matrigel=grafting of matrigel based HA/PCL scaffold; M + B=grafting of matrigel based HA/PCL scaffold with BMP-2; M + B + V=grafting of matrigel based HA/PCL scaffold with BMP-2 and VEGF, MSC=grafting of matrigel based HA/PCL scaffold with BMP-2, VEGF and mesenchymal stem cell.