Table 1.
Effect of matrigel-based HA/PCL scaffold with osteogenic, angiogenic factors and mesenchymal stem cell on bone volume and bone mineral density in a rat segmental defect model at 4 weeks after surgery
Group | Bone Volume (%) | Bone mineral density (g/mm3) |
Control | 12.646 ± 2.629 | 0.070 ± 0.020 |
Matrigel | 21.159 ± 3.154* | 0.100 ± 0.032 |
M + B | 24.383 ± 4.630* | 0.136 ± 0.038 |
M + B + V | 35.201 ± 3.021**.a | 0.231 ± 0.030** |
MSC | 27.262 ± 3.479** | 0.171 ± 0.045* |
P<0.05 as compared with the Control group.
P<0.01 as compared with the Control group.
P<0.05 as compared with the M + B group.
Values are expressed in mean ± S.D. (n=6).
Control=no graft with 5 mm femoral segmental defect; Matrigel=grafting of matrigel based HA/PCL scaffold; M + B= grafting of matrigel based HA/PCL scaffold with BMP-2; M + B + V=grafting of matrigel based HA/PCL scaffold with BMP-2 and VEGF, MSC=grafting of matrigel based HA/PCL scaffold with BMP-2, VEGF and mesenchymal stem cell.